EP 54: 5 Trials that will change your practice: Review of ESC 21 with Dr Purvi Parwani
EP 54: 5 Trials that will change your practice: Review of ESC 21 with Dr Purvi Parwani

Average (ratings)
No ratings
 
  Your rating

In this week’s episode Dr Ankur Kalra’s guest is Dr. Purvi Parwani, Director of Women’s Cardiovascular Disease Clinic and Assistant Professor at Loma Linda University Medical Center.
In this special ESC 2021 edition of Parallax, Ankur asks Purvi to review the highlights of the congress. Purvi summarises the design and findings of the trials and their importance in the treatment of patients. Ankur and Purvi discuss how the novel data presented at ESC will inform their practice.

Trials covered in detail include

• SSaSS: Effect of Salt Substitution on Cardiovascular Events and Death,
• STEP: Intensive vs. standard blood pressure control among older hypertensive patients
• EMPEROR-Preserved and Pooled: Effect of empagliflozin on cardiovascular death and heart failure hospitalisations in patients with heart failure with a preserved ejection fraction, with and without diabetes,
• LOOP: Screening for AF with an implantable loop recorder to prevent stroke compared with results of the STROKESTOP trial,
• IAMI: Influenza Vaccination after Myocardial Infarction randomised trial.

What are the take-home messages of ESC 21? How can we utilise the findings in our practice? What are the questions that need further investigation?

Questions and comments can be sent to “podcast@radcliffe-group.com” and may be answered by Ankur in the next episode. Guest @purviparwani, hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.


Read MoreRead Less
Share
Brought to you by Edwards: www.edwardstavr.com

Brought to you by Edwards: www.edwardstavr.com

Read MoreRead Less
Up Next
EP 55: 5 Interventional trials that will change your practice: Review of ESC 21 with Dr Mirvat Alasnag
EP55 • Sep 28, 2021 • 53m 38s
In the second ESC 2021 episode of Parallax, Dr Ankur Kalra’s guest is Dr. Mirvat Alasnag, interventional Cardiologist and Director of Catheterization Laboratory at the King Fahad Armed Forces Hospital (KFAFH) in Saudi Arabia. Dr Alasnag was a programme committee member at this year’s ESC and regional PI of one of the late-breaking trials presented.
Read More
All Episodes
Burnout & Resilience With Kavitha Chinnaiyan: Practicing Self-Care
EP11 • Apr 23, 2020 • 55m 33s
What are the key pillars of self-care and what do dirty windshields have to do with it? How can you take meditation “off the matt”? What has chronobiology and Ayurveda taught us about working with, rather than against, our circadian rhythm?



In the final episode of our burnout and resilience series, Kavitha and Ankur give you some practical tools of self-care to help you avoid burnout. Kavitah Chinnaiyan, MD, is an award-winning author and, Cardiologist and Director of Cardiac CT Research at Beaumont Health, MI. Send us your thoughts to this episode for Ankur to share in future episodes: podcast@radciffe-group.com. Guest @ChinnaiyanMD.



Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
Read More
Burnout & Resilience Kavitha Chinnaiyan Mindfulness
EP10 • Apr 23, 2020 • 46m 17s
What does mindfulness have to do with burnout? Is our definition of success driving our stress and anxiety? How can we channel our ego into something positive?



In our second episode on burnout and resilience, Kavitah Chinnaiyan, MD, and Ankur take a deeper dive into mindfulness and training the brain to move from Default-Mode to Task-Positive Networks. Kavitah is an award-winning author and, Cardiologist and Director of Cardiac CT Research at Beaumont Health, MI. Send us your thoughts to this episode for Ankur to share in future episodes: podcast@radciffe-group.com. Guest @ChinnaiyanMD.



Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
Read More
Burnout & Resilience With Kavitha Chinnaiyan
EP09 • Apr 23, 2020 • 43m 23s
How do you nurture resilience in the midst of competition, envy and individualism? What is moral injury? Is the current healthcare landscape driving physicians to burnout? Are we too focused on data and study results? These are some of the questions discussed by Kavitah Chinnaiyan, MD, award winning author and Cardiologist and Director of Cardiac CT Research at Beaumont Health, MI, and host Ankur, in the first episode of this three-part series on burnout and resilience. Send us your thoughts to this episode for Ankur to share in future episodes: pocast@radciffe-group.com. Guest @ChinnaiyanMD.



Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO. 
Read More
Diversity, Inclusion & Leadership With Madhav Swaminathan
EP08 • Apr 23, 2020 • 43m 23s
Madhav Swaminathan joins Ankur Kalra for a dynamic conversation about diversity, inclusion and leadership. Madhav shares how, as President of large organisation like the American Society of Echocardiography, he works to create an inclusive platform with opportunities for individuals from diverse backgrounds.



Ankur and Madhav also discuss positive traits of leadership, why we should embrace failure and the importance of mentorship throughout all stages of one’s medical career. Send us your comments to this episode for Ankur to share in future episodes: pocast@radciffe-group.com. Guest @mswami001.



Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
Read More
Demystifying The Wall Portraits In Medical Halls
EP07 • Apr 23, 2020 • 19m 50s
Following the recent controversy surrounding physician portraits displayed in medical hallways, Ankur spoke to Harriette GC Van Spall MD to unpick this hot topic brought back to life by a recent article penned by Jeffrey Flier (former Dean of Harvard Medical School) in The Boston Globe.



Harriette is an Associate Professor of Medicine at the Department of Medicine, Cardiology and the Department of Health Research Methods, Evidence and Impact at McMaster University and the Population Health Research Institute in Hamilton, ON, Canada. In this episode, Ankur and Harriette discuss why this issue is so contentious, what the current state of medical walls represents, why this may be an issue and what alternative medical walls could look like. Harriette also shares her thoughts on how this topic relates to the maintenance of hierarchical power structures in academic institutions, calling for more collaborative leadership and management styles. Guest @hvanspall.



Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO. 
Read More
Plant-Based Diet & Cardiovascular Health
EP06 • Apr 23, 2020 • 34m 28s
In celebration of this month’s ‘National Eat Your Vegetables Day’, this week’s guest is @TheVeggieMD, one of the most prominent physicians on social media! Dr Danielle Belardo MD is a Cardiology Fellow, American Board of Internal Medicine certified and a member of the American College of Cardiology Nutrition and Lifestyle Sub-Committee.



In this episode, Ankur and Danielle speak about the evidence in favour of a whole-food plant-based diet to improve cardiovascular health, the ACC prevention guidelines, how to talk to patients about positive dietary change, the issue of lack of nutrition training in cardiovascular fellowships and what Danielle’s diet looks like as a busy whole-food plant-based cardiology fellow. On her own podcast ‘Nutrition Rounds’ Danielle has discussions about evidence-based plant-based nutrition with physicians who are leading experts in nutrition and health.



Hosted by @AnkurKalraMD. Produced by @RadcliffeCardiology.
Read More
Drug-Coated Balloons Small-Vessel CAD Brilakis - Megaly
EP05 • Apr 23, 2020 • 27m 43s
Listen to our first episode with two guests! Ankur spoke with Emmanouil S Brilakis, MD and Michael Megaly, MD from the Minneapolis Heart Institute, Abbott Northwestern Hospital about their article on the role of drug-coated balloons in small-vessel coronary artery disease (SVD) published in US Cardiology Review 13.1. Percutaneous coronary intervention of SVD remains challenging due to difficulties with device delivery and high restenosis rate, making drug-coated balloons an attractive emerging option in patients with SVD.



In this brilliant conversation, Ankur, Emmanouil and Michael unravel the potential advantages, challenges and practical realities of using drug-coated balloons in SVD, and the findings of the latest randomised controlled trials studying this area.



Hosted by @AnkurKalraMD. Produced by @RadcliffeCardiology. [Disclaimer: The use of drug-coated balloons in coronay intervention is still off-label; it has not been approved by the FDA.]
Read More
04: J Dawn Abbott On Recent Developments In Percutaneous Coronary Intervention
EP04 • Apr 23, 2020 • 34m 58s
We have observed a lot of developments in percutaneous coronary intervention (PCI) over the past 12 months with the publication of various studies and trials. This week, Ankur spoke with J. Dawn Abbott, MD, Associate Professor of Cardiology at Warren Medical School of Brown University about her recently published US Cardiology Review 13.1 article on the significant developments in PCI over the past 12 months.



Dawn is an associate editor of the journal Circulation: Cardiovascular Interventions and is widely known for her research program on PCI and peripheral arterial disease (PAD). Ankur and J. Dawn discuss multiple trials/studies that were published in 2018, including ORBITA, PIONEER-II and ABSORB. J. Dawn also shares her thoughts on the latest stent technologies.



Hosted by @AnkurKalraMD. Produced by @RadcliffeCardiology.
Read More
03: Athena Poppas On Effective Management Of Hypertension
EP03 • Apr 23, 2020 • 29m 43s
This week’s podcast guest needs no introduction! Prof Athena Poppas is one of the most widely known cardiologists in the US and current Vice-President of the American College of Cardiology! Ankur spoke to Athena about her recently published US Cardiology Review 13.1 article on whether early management of hypertension by GPs can improve outcomes.



They discuss the importance of preventative medicine, their experience of reducing hypertension with non-pharmaceutical and pharmaceutical methods, and the significance of the integrated “team approach” when treating comorbid conditions such as hypertension. Athena also shares her thoughts on cardiologists’ responsibility to shape their patients’ lifestyle choices.



Hosted by @AnkurKalraMD. Produced by @RadcliffeCardiology.
Read More
High-Sensitivity Cardiac Troponin ACS
EP02 • Apr 23, 2020 • 29m 55s
Ankur is back with his second #AudioArticle! This week he spoke with Santiago Garcia from the Minneapolis Heart Institute about Santiago’s US Cardiology Review 13.1 article on the role of high-sensitivity cardiac troponin (hscTn) assays and their ability to rapidly rule in or rule out acute coronary syndrome (ACS) with improved sensitivity.



Chest pain is one of the most common reasons for an emergency room visit in the US, with almost 6 million ER visits annually, yet there is no consensus on how to compare the results from various hscTn assays. Tune in to hear Santiago outline the advantages and limitations of using hscTn as a standard biomarket to evaluate patients with suspected ACS in the ER.



Hosted by @AnkurKalraMD. Produced by @RadcliffeCardiology.
Read More
21: The “Interventional Intensivist” With Ann Gage
EP21 • Apr 23, 2020 • 32m 18s
We can count on our fingertips how many interventional intensivists exist in the US.



In this episode Ankur Kalra, MD meets with Dr Ann Gage, Cleveland Clinic’s first ‘interventional intensivist’. She discusses her unique skill set, what it means to be an interventionalist in the cath lab but also an expert in cardiovascular intensive care and advocates why such a unique skill set and critical care training are required in today’s modern medicine.



Listen to this engaging discussion between them on the challenges of being a woman in cardiovascular medicine today.



Submit your question to Ankur via: podcast@radciffe-group.com. Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
Read More
Staging Of Aortic Valve Disease: A Novel Approach
EP20 • Apr 23, 2020 • 41m 53s
Dr Cavalcante meets with Ankur Kalra, MD to discuss his recent review published in US Cardiology Review 13.2; on a new aortic stenosis staging system that has important implications for clinical outcomes following aortic valve replacements to aid the treatment of aortic stenosis.



Listen to this, as well as an overview on his interesting childhood and his views on the future of cardiac imaging to treat TAVR.



Submit your question to Ankur via: podcast@radciffe-group.com. Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
Read More
19: Women In Cardiology With Kendra Grubb
EP19 • Apr 23, 2020 • 41m 30s
The first female cardiac surgeon qualified in the 1960’s. Today there are only 4.5% women in cardiology and only 4% in thoracic surgery. Ankur Kalra meets with Dr Kendra Grubb, the first women to be trained at the University of Virginia, US, on cardiothoracic surgery and the 250th board certified women in thoracic surgery.



Her recent post on social media went viral. It was a photo of an all-women surgical team carrying out a complex structural heart procedure. It had over 100,000 views and was seen by people in over 75 different countries. It’s clear from this online reaction, that now is the time for women to be recognised for the work they are doing in medicine.



Listen to this engaging discussion between them on the challenges of being a woman in cardiovascular medicine today.



Submit your question to Ankur via: podcast@radciffe-group.com. Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
Read More
18: The Year 2019 In Review With Sukh Nijjer
EP18 • Apr 23, 2020 • 1h 58m 55s
In our final episode of the year, Ankur has an long conversation with Sukh Nijjer from Imperial College London about the most impactful, exciting and controversial clinical trials of 2019. Sukh and Ankur also discuss how these trials might change practice in the future, and how practice patterns and decisions differ between the US and the UK. In light of an emerging trend of shared decision making between physicians of different specialities and patients with a vast amount of information at their fingertips, Sukh and Ankur examine what tools they use to reconcile the growing data from clinical trials.



Trials discussed in detail include those presented at the ACC in New Orleans: PARTNER 3 & Evolut Low Risk on TAVR/TAVI, and SAFARI & COAPT on radial vs femoral access; presented at the ESC in Paris: THEMIS and ISAR-REACT 5 on DAPT post-PCI, DAPA-HF on SGLT2i’s for heart failure, and COMPLETE on PCI of non-culprit lesions in STEMI; presented at TCT in San Francisco: TWILIGHT on DAPT post-PCI, and EXCEL at 5 years on PCI vs CABG in left main CAD; and finally, presented at AHA in Philadelphia: ISCHEMIA on medical vs invasive approaches in ischemic events. Submit your question to Ankur via: podcast@radciffe-group.com.



Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
Read More
Rasha Al-Lamee On ORBITA, ISCHEMIA, Coronary Revascularisation
EP17 • Apr 23, 2020 • 38m 2s
Recorded before the American Heart Association (AHA) Scientific Sessions 2019, Ankur is joined by Rasha K Al-Lamee, Interventional Cardiologist at Imperial College Healthcare NHS Trust in London and Study Director of the Objective Randomised Blinded Investigation with Optimal Medical Therapy of Angioplasty in Stable Angina (ORBITA) trial. Rasha talks about how she got into academia, the significance of her end-of-training PhD, and what led to the genesis of ORBITA.



Ankur and Rasha also discuss the findings and unanswered questions of ORBITA, and how recent research in coronary revascularisation and stable ischemic heart disease has (or has not) changed their clinical practice. Finally, in anticipation of its presentation at AHA 2019, Rasha gives an overview of the International Study of Comparative Health Effectiveness with Medical and Invasive Approaches (ISCHEMIA). Submit your question to Ankur via: podcast@radciffe-group.com.



Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
Read More